The secretory pathway: exploring yeast diversity
نویسندگان
چکیده
منابع مشابه
The early secretory pathway contributes to autophagy in yeast.
Autophagy is a starvation response in eukaryotes by which the cell delivers cytoplasmic components to the vacuole for degradation, and is mediated by a double membrane structure called the autophagosome. We have previously proposed that the specific combination of COPII like components, including Sec24p, is required for autophagy (Ishihara, N. et al. (2001) Mol. Biol. Cell, 12: 3690-3702). The ...
متن کاملMyristoylation of proteins in the yeast secretory pathway.
Protein myristoylation was investigated in the yeast secretory pathway. Conditional secretory mutations were used to accumulate inteRmediaries in the pathway between the endoplasmic reticulum and Golgi (sec 18, 20), within the Golgi (sec 7), and between the Golgi and plasma membrane (sec 1, 3, 4, 5, 6, 8, 9). The accumulation of vesicles was paralleled by the enrichment of a defined subset of p...
متن کاملIlluminating the secretory pathway
Proteins destined for secretion, the plasma membrane or membranous cellular organelles enter the secretory pathway in the endoplasmic reticulum (ER) and move via the Golgi complex to the trans-Golgi network, where they are sorted and transported to their final destination. Malfunction in this pathway may lead to the breakdown of cellular organelles, cell polarity, overall cellular architecture ...
متن کاملThe Ypt1 GTPase is essential for the first two steps of the yeast secretory pathway
Small GTPases of the rab family are involved in the regulation of vesicular transport. The restricted distribution of each of these proteins in mammalian cells has led to the suggestion that different rab proteins act at different steps of transport (Pryer, N. K., L. J. Wuestehube, and R. Sheckman. 1992. Annu Rev. Biochem. 61:471-516; Zerial, M., and H. Stenmark. 1993. Curr. Opin. Cell Biol. 5:...
متن کاملThe Yptl GTPase Is Essential for the First Two Steps of the Yeast Secretory Pathway
Small GTPases of the rab family are involved in the regulation of vesicular transport. The restricted distribution of each of these proteins in mammalian cells has led to the suggestion that different rab proteins act at different steps of t ransport (Pryer, N. K., L. J. Wuestehube, and R. Scheckman. 1992. Annu Rev. Biochem. 61:471-516; Zerial, M., and H. Stenmark. 1993. Curr. Opin. Cell Biol. ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: FEMS Microbiology Reviews
سال: 2013
ISSN: 1574-6976
DOI: 10.1111/1574-6976.12020